Driving chemical innovation in fluorescent dyes for research and clinical diagnostics — fluorogenic, multiplexable, and remarkably easy to use.
>95%
Accuracy
1 hr
Result time
>25%
Quantum yield
Most lipophilic dyes are highly hydrophobic and need DMSO or ethanol. Those solvents introduce artifacts and nanoaggregates that corrupt analysis of small particles like exosomes. Acoerela dyes are engineered to dissolve cleanly in water.
Solvent-based — prone to clumping
Monomeric — clean in aqueous buffer
Flip binding on. Conventional dyes keep glowing with background noise — Acoerela stays dark until it finds its target, then fluoresces clean.
Target bound — signal on
Stack through the core advantages that set Acoerela dyes apart from every conventional probe.
High quantum yield above 25%. Fluorescence increases dramatically only when the dye binds its target, where the surrounding environment becomes hydrophobic. The stark contrast between bound and unbound states delivers a clean "light-on" mechanism.
The Acoerela chromophore platform derives up to five distinct colors. We continuously expand excitation and emission profiles to unlock richer multiplexing across a wide range of applications.
Highly water soluble with no micelle or nanoparticle formation when reconstituted in aqueous buffer — unlike PKH26, DiR and DiD dyes that drive false positives in flow cytometry of exosomes.
From exosomes to in vivo tumor tracking — Acoerela dyes are validated across the assays researchers run every day.
EVs & ExosomesReliable labelling of exosomes without nanoaggregate false positives in flow cytometry.
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MicrobiologyDistinguish gram-positive and gram-negative populations with selective fluorogenic staining.
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Cell BiologyBright, stable plasma-membrane labelling for live-cell and confocal imaging.
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ProliferationFollow proliferation across generations with even dye partitioning at each division.
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HematologyGentle, water-soluble labelling of RBCs for circulation and clearance studies.
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In Vivo ImagingDeep-tissue in vivo imaging in the second near-infrared window for tumor tracking.
Discuss this applicationAcoerela dyes are validated across the analytical platforms researchers rely on every day.
Clean single-peak populations with minimal background from monomeric, non-aggregating dyes.
High-contrast per-particle imaging distinguishes labelled vesicles from debris and artifacts.
Deep-tissue fluorescence enables longitudinal tumor tracking well beyond conventional windows.
Acoerela dyes hold up across long-duration experiments — from incubation to multi-week in vivo tracking.
2 h
Incubation
Rapid membrane insertion in buffer
4 h
Signal peak
Maximum fluorogenic brightness
8 h
Stable
Retained labelling, low leakage
14 d
Cell tracking
Division-tracked in vivo
26 d
NIR-II tumor
Longitudinal deep-tissue imaging
A growing catalog of water-soluble fluorogenic probes and calibration standards.
100 tests
Far-red fluorogenic dye for high-contrast labelling with minimal autofluorescence.
100 tests
Blue-excitable dye ideal for multiplexed panels and imaging workflows.
Membrane labelling
Membrane labelling dye family for mammalian cells, bacteria and vesicles.
Reference liposomes
Reference liposomes for standardised sizing and fluorescence calibration.
Spectral data, protocols, and application notes for the entire water-soluble dye platform — everything you need to plan your next experiment.
Acoerela began as academic researchers from a diversity of scientific backgrounds, united by a unique chemistry technology and a mission to serve research and industry alike.
Founding Researcher
Materials Chemistry
Founding Researcher
Biophysics
Founding Researcher
Life Sciences
Founding Researcher
Chemical Design
Tell us about your application and our scientists will get back to you with the right dye and protocol.